Cytogenetic Support: Your Genomic Research, Our Chromosome Expertise
Applied Genetics Laboratories has been offering cell characterization services to companies and research institutes in the areas of medicine, pharmaceuticals, tissue engineering, and vaccine production since 1984. The cell characterization services offer cytogenetic analysis including karyotyping, chromosome aberration analysis, chromosome count, and determination of modal chromosome number as well as isoenzyme analysis for species identification. The G-banded karyotypes provided by AGL are high-quality images suitable for publication. All services comply with the FDA Good Laboratory Practice (GLP) regulations and can be tailored to the client’s specific needs.
Hybloc™ Competitor DNA, which is Cot-1 DNA®, is the repetitive sequence fraction of genomic DNA. Hybloc™ DNA may be effectively substituted for any other competitor DNA (i.e., Cot-1 DNA®, salmon sperm, etc.) for fluorescence in situ hybridization (FISH), Southern blots, microarray technology, or any other protocol requiring competition to prevent repetitive DNA from binding to the target. Hybridization with Hybloc™ competitor DNA shows a marked increase in signal intensity and a significant decrease in the amount of background noise associated with non-specific binding of repetitive DNA.
Male or female human metaphase slides are available for use in various fluorescence in situ hybridization (FISH) protocols. Slides for other species, suitable for FISH protocols, are available on special request.
®Cot-1 DNA is a registered trademark of Invitrogen Corporation
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