Applied Genetics Laboratories, Inc. (AGL) is
a privately held biotechnology company specializing in G-banded karyotyping, cytogenetic
analysis, isoenzyme analysis, COT-1 DNA® products and normal human metaphase
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Cell Line Characterization,
including Isoenzyme and Karyotyping / Cytogenetic Analyses
Applied Genetics has been
offering cell characterization services to companies and research institutes in the areas
of medicine, pharmaceuticals, tissue engineering and vaccine production since
1984. The cell characterization service offers a cytogenetic service including
karyotyping, chromosome aberration analysis, chromosome count, and determination of modal
chromosome number, and offers isoenzyme analysis service for species identification.
The karyotyping service provides G-banded karyotypes suitable for publication. All
services comply with the FDA Good Laboratory Practice (GLP) regulations and can be
tailored to the clients specific needs.
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Hybloc™ Competitor DNA,
which is COT-1 DNA®, is the repetitive sequence fraction of genomic DNA.
Hybloc™ DNA may be effectively substituted for any other competitor DNA (ie., COT-1
DNA®, salmon sperm, etc.) for in situ hybridization, Southern blots,
microarray technology or any protocol requiring competition to remove repetitive DNA from
binding to the target. Hybridization with Hybloc™ competitor DNA shows a marked
increase in signal intensity and a significant decrease in the amount of background noise
associated with non-specific binding of repetitive DNA.
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Male or female human metaphase
slides for use in various FISH protocols.
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